Tag Archives: Timothy Brown

October Round Up

It’s time for another roundup, and what a roundup it is, all 23,000 words of it! we hope you’ve got some reading time set aside.  Here are the posts from October wrapped up together in case you’ve missed anything.  Or if you prefer, you can download the whole lot as a pdf for your viewing leisure off line.

Have you subscribed yet? Or would you prefer to follow @LASSLeics on Twitter to get your info? Either is a good way to stay up to date about LASS and HIV news from Leicester, Nationally and International.

You may just be a casual browser here for the first time? – Stay a while, soak it in or dive in to a random post at your leisure.

Poverty-Stricken Families Join a Lengthening Queue for Food Handouts

Fancy a Curry? – Join Us For Social Evening At The Cuisine Of India Restaurant

HIV Could Spread If Birth Control Injections Increase, Warn Scientists

The Red Ribbon Dress 2011/2012 Project

Commonwealth Publication Raises Concerns Over Rights of HIV and AIDS Carers

A Message of Hope for a HIV Cure from Timothy Brown

HIV and AIDS Stigma Defies Traditional Care in the Pacific

AIDS Treatment is Good Value for Money, Says New Study

Steve Jobs and HIV Apps for iOS

THT Asks Government to Legalise and Regulate HIV Home Testing Kits

UKBA proposals to deny entry or stay to migrants with NHS debt: a public health disaster waiting to happen

Questions on Tactics to Prevent HIV [PrEP]

Gonorrhea Possibly Becoming ‘Untreatable’

Increase In Life Expectancy for People Living With HIV

HIV and TB activist Winstone Zulu has Died

How Good is Sex Education in Schools?

Dating, HIV & You

Discussions with a Dietitian: Sugary Foods

Testing people with conditions suggesting HIV could pick up more recent infections, Europe-wide study finds

New MSM Panel report from Sigma Research

Blind Faith: HIV Prayer Cure Claims Three Deaths

Pill Box Organisers Increase HIV Patients’ Adherence & Improve Viral Suppression

Antiretroviral Drugs Work – This Is Why You Should Take Them!

People Get HIV Through Unprotected Sex, Not Because They’re Going For Fish Pedicures!

Pill-Popping Reminder App for iOS!

What Can We Do Now to Speed Up HIV Cure Research?

New HIV Diagnoses – UK National Overview 2001 – 2010

What About HIV? – Infographic

Gaddafi’s HIV Shakedown

Vote for Pozitude! The Website by Children Living With HIV

HIV Diagnosis Progress Hampered by Inaccurate Online Information

Preventing HIV with social media and mobile phones

Religion, HIV & Mental Health

Leicestershire Community Calendar 2012

Consultation To Start On Managing Urgent Care In Loughborough

LASS Secures Funding To Help Make The Big Society A Reality In The East Midlands.

Other Interesting Stuff We Didn’t Post But Want You To Know

Download all of this as a PDF.

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What Can We Do Now to Speed Up HIV Cure Research?

As most of you know, the case of Timothy Brown (aka The Berlin patient), a person who got cured of HIV and leukemia 5 years ago, has jolted a new energy and hope into the search for a HIV cure.  But most people with HIV, policymakers and potential funding sources are not fully aware of this case and what the new movement for a search for a cure are all about. So, Nelson Vergel, writer for The Body.com decided was to travel around the country to interview key players in advancing this field and make a short video that could serve as a catalyst for awareness and change.

This short video, done with a very low budget with the help of his activist friend Greg Fowler, is only part of a longer, more detailed documentary to be finished before World AIDS Day this year, the 30-year anniversary of the first AIDS cases.

Please watch it and forward it to your friends. Please follow the suggestions made in that video and become part of the cure! Everyone can do something now to raise awareness and funds not only for research but also for advocacy and education in this important new and expanding area.

Via TheBody.com

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A Message of Hope for a HIV Cure from Timothy Brown

Timothy Brown revealed himself last year as the "Berlin Patient." His HIV was cured through a bone marrow transplant from a donor born with a genetic mutation resistant to the virus. Courtesy of Timothy Brown

He’s been called the “Berlin Patient” and the man who was cured of HIV.  Today, Timothy Brown is speaking in Houston tonight about the bone marrow transplant from a donor born with resistance to the infection that essentially cured his HIV.

Brown, 45, was diagnosed with HIV in 1995. For more than a decade, he managed the virus with antiretroviral medications while continuing his career as a German-English translator in Berlin.

He was diagnosed with leukaemia in the summer of 2006. Brown was treated with chemotherapy but decided to wait on receiving stem cells from a bone marrow transplant believing it was too dangerous. His oncologist was concerned about the delay, predicting the blood cancer might return. The doctor was right. The leukaemia was back by the end of the year.

Brown underwent a stem cell transplant via bone marrow in February 2007.

“I had a lot of possible donors, but the doctor decided to look for a person that didn’t have the CCR5,” Brown said in a phone interview from San Francisco, where he now resides.

CCR5 is a protein or co-receptor that connects with CD4 cells or primary white blood cells in the immune system. That link is a pathway that allows HIV to cause infection. Without CCR5, a genetic variation, HIV can’t invade the immune system. About 10 percent of Northern Europeans have the mutation.

Brown’s case was documented in a February 2009 issue of The New England Journal of Medicine.

“They found a donor who carried a well-known set of mutations that makes one resistant to HIV,” said Dr. Thomas Giordano, a longtime HIV specialist and medical director of Houston’s Thomas Street Health Center – the Harris County Hospital District‘s HIV/AIDS treatment facility. “Two things are required: CD4, which everyone has, and CCR5, which almost everyone has. If one of them is absent, HIV can’t get in.”

The leukemia returned again and Brown had a second stem cell transplant in 2008 from the same donor.

So, has Brown really beaten HIV?

“He’s cured,” said Giordano, also an associate professor of medicine at Baylor College of Medicine. “I think it’s pretty well accepted that he’s cured. Just like any other chronic illness, you have to reserve a little bit of caution. Could his HIV come back? It’s been theoretically possible, but it’s pretty clear it should have come back by now, but it hasn’t.”

Giordano said the Brown case demonstrates the promise of gene therapy in the fight against HIV/AIDS, but he cautions that Brown is one person in a single experiment.

“A bone marrow transplant, especially from an unrelated donor, is a risky proposition,” Giordano said. “If you have HIV and you are healthy and your viral load is undetectable, your survival is approaching that of someone who does not have HIV. To take the risk of a bone marrow transplant makes no sense at all – unless you have leukemia.”

Even with this advancement, a cure remains “many, many years away,” the doctor added.

“What it has done is quickened the pace of investigation of gene therapies to treat HIV. If you could convert people from having CCR5 to not having CCR5 in some way other than a bone marrow transplant, could you cure people? That’s the avenue that’s being researched now.”

Giordano added that Brown’s case offers hope for people living with HIV/AIDS.

“He is the first person to be cured of HIV. It was an extreme situation and extreme therapy, but it does give you some hope that we can learn enough from him to use a similar genetic approach that would be much safer to slow down, if not cure, the disease or make the need for medication less or something to help people out.”

Brown is speaking from tonight, 23:00 to 02:30 (gmt) (18:00 to 21:30 in Houston) Treebeards, 315 Travis, as part of a limited-seating cure for more information.

Here’s another recent piece about Brown from the Los Angeles Times.

Original Article by Cindy George at Chron.com

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